Manuscripts submitted for publication should be formatted in 12 (or 14) pt double-spaced Times New Roman. It should also be formatted with justified margins in a single column. Bold face, italics, superscripts, subscripts, and other text formatting styles are allowed when appropriate. Spelling and grammar-checking tools are strongly advised to avoid errors. Pages should be numbered at the bottom middle, and lines should also be continuously numbered throughout the text. 

Double-Blinded Review Process:

This journal applies a double-blinded reviewing process that conceals the identities of the author and reviewer from each other. Therefore, the following files should be submitted separately:

I. Cover page:

It should present the title of the research, the name(s) of the author(s), their affiliations, and acknowledgments (if any), besides the address and the e-mail of the corresponding author.

II. Main manuscript (no personal details):

Authors’ names, affiliations (or any other personal information) should not be included in the main manuscript file.

Article structure:

Subdivision

It is recommended that authors keep their papers concise, as lengthy ones with several tables and figures may need to be shortened before review or publication. Even though there is no stipulated length for a manuscript, it is better to limit it to 5,000 words  and a manuscript should provide a minimum of 30 references in case of original article, and 50 references in case of review article

The Main Manuscript file should contain the following sections:

1. Abstract, Keywords
2. Introduction
3. Material and methods (Experimentation, Methodology followed, and Patients & methods)
4. Results (can be merged with Discussion)
5. Discussion
6. Conclusion
7. Acknowledgment (if any)
8. Conflict of Interest
9. Funding
10. References
11. Tables
12. Figures
13. Abbreviation list

Note: Each section’s heading should be written in UPPERCASE format (e.g., ABSTRACT, KEYWORDS, MATERIALS AND METHODS, etc.)

ABSTRACT:

The context or background of the research, the aim of the study, the main procedures followed (selections of study subjects or laboratory animals, and observational & analytical methods), the key findings (their effect magnitude and their statistical significance, if applicable), and the main conclusions should be stated in a structured abstract using appropriate headings. It should point out some authentic aspects, the contribution(s) of the study. Authors should avoid non-common abbreviations unless they are defined when first mentioned in the abstract. A one-paragraph, 300-word abstract should have the following:

For Original Papers: 

• Introduction: a description of the topics’ mechanisms, their background, and/or the extent of their connection to the problem. 
• Objectives: an explanation of the purpose(s). What is meant to be proven by the research?
• Materials and methods: a brief description of the design of the experiment and the related statistical tests. 
• Results: a detailed report of key findings.
• Conclusion: an analysis of results, showing a clear connection to the purpose.

For Review Articles:

An abstract should follow the structure of:

Background

Aim of the Review

Main Scientific Concepts of Review The background of the review and the reason why it is being conducted should both be provided in the 300-word abstract.

It should also point out the important findings of the review.

• KEYWORDS: 4 to 6 keywords, separated by commas and used for indexing purposes.
• INTRODUCTION: It should explain the importance of the study and the rationale behind conducting it. Background information should be discussed briefly with relevant topics. 
• MATERIAL AND METHODS: (Experimentation, Methodology followed, or Patients and methods) The experimental section needs to have all the details required to ensure reproducibility, so authors should try to keep their descriptions of the experiments as concise as possible. Only significant modifications should be provided, regarding the already-published related methods. If you obtain any chemicals, reagents, strains, or other items from a supplier, include his business, location, and country in the vendor information Appropriate test(s), hypothesized p-values, or significant levels should be stated and used in the statistical analysis.
• RESULTS: The study’s results should be concise and precise. Limit the data provided by figures and tables to only what is necessary to understand the study's conclusions and message. Avoid using the same data in tables and figures. Text, tables, and visuals presenting the results should follow a logical order.
• DISCUSSION: This section is an exploration of the importance of the study’s results, not a replication of them. It should include a discussion of the consequences and limitations of the findings, to what extent they correlate with relevant data, and recommendations for future work. The discussion should start with the main findings of your study. 

a)- A summarization of the main findings (be they primary or secondary).

b)- An explanation of the consequences that are based on evidence (is there a systematic review to consult; if not, how can this be done in a reasonable manner here? 

c)- The argument raised by this study.

d)- Further work recommendations (for the research’s contribution, demonstrating methods, and clinical trials).

CONCLUSION(S): The study’s main conclusion(s) should be given in a separate brief statement. A clear connection should be made between the conclusion and the objectives of the study. Mention new hypotheses if justified, and recommendations if appropriate. Avoid any inadequate or unproven statements or conclusions.

Illustrations: Illustrations should be less than six. Artwork files should be in one of (MS Office files, EPS, or TIFF) formats and of high resolution (300 dpi). They should also be numbered using Arabic numerals, as Fig. 1, Figs. 2, 3-5. Illustrations should be introduced by describing clear legends. Tables, figures, and schemes should be ordered numerically. If chemical formulations are replaced, this should be stated. Illustrations and figures’ legends should be uploaded as separate sheets at the end of the manuscript.

Tables: Tables should be less than six, including only essential and relevant data, and uploaded on separate sheets.

References: Text: Indicate references with Arabic numerals in parentheses, which are arranged in the order of appearance throughout the text (Vancouver style). For instance, [4] or [7-10, 13,15]. Actual authors can be referred to, but the reference number(s) should always be provided. List: Number the references (e.g., [2]) in the list in the order in which they appear in the text. Journal names should be abbreviated according to Index Medicus journal.

Abbreviations: http://www.nlm.nih.gov/tsd/serials/lji.html.

Examples of references (if there are 6 or fewer authors, list all; if 7 or more, list the first 6 and add "et al.")

Research Ethics: Research Involving Human Subjects If the research involves human subjects, human material, human tissues, or human data, the statement, which includes the project identification code, date of approval, and name of the ethical committee, should be declared and cited in the Methods Section of the article. If research involves human subjects, authors are encouraged to seek advice from the ethical committee. Research Involving Cell Lines If the research involves cell lines, the authors should state their origin. For generated cell lines, the source should be cited, and references should be given to either a published paper or to a commercial source. If the gifted from another laboratory new cell lines were used, details of the ethical committee approval should be provided. Please attach the Research Ethics Committee approval document, and add the approval code inside the manuscript (in the Materials and Methods) section. The patient's informed consent must be attached among attachments if it is used.